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Novel genes upregulated when NOTCH signalling is disrupted during hypothalamic development

BACKGROUND: The generation of diverse neuronal types and subtypes from multipotent progenitors during development is crucial for assembling functional neural circuits in the adult central nervous system. It is well known that the Notch signalling pathway through the inhibition of proneural genes is...

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Detalles Bibliográficos
Autores principales: Ratié, Leslie, Ware, Michelle, Barloy-Hubler, Frédérique, Romé, Hélène, Gicquel, Isabelle, Dubourg, Christèle, David, Véronique, Dupé, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880542/
https://www.ncbi.nlm.nih.gov/pubmed/24360028
http://dx.doi.org/10.1186/1749-8104-8-25