Evolution of the Chalcone Isomerase Fold from Fatty Acid-Binding to Stereospecific Enzyme

Specialized metabolic enzymes biosynthesize chemicals of ecological importance, often sharing a pedigree with primary metabolic enzymes(1). However, the lineage of the enzyme chalcone isomerase (CHI) remained a quandary. In vascular plants, CHI-catalyzed conversion of chalcones to chiral (S)-flavano...

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Detalles Bibliográficos
Autores principales: Ngaki, Micheline N., Louie, Gordon V., Philippe, Ryan N., Manning, Gerard, Pojer, Florence, Bowman, Marianne E., Li, Ling, Larsen, Elise, Wurtele, Eve Syrkin, Noel, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880581/
https://www.ncbi.nlm.nih.gov/pubmed/22622584
http://dx.doi.org/10.1038/nature11009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880581/
https://www.ncbi.nlm.nih.gov/pubmed/22622584
http://dx.doi.org/10.1038/nature11009

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