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Evolution of the Chalcone Isomerase Fold from Fatty Acid-Binding to Stereospecific Enzyme

Specialized metabolic enzymes biosynthesize chemicals of ecological importance, often sharing a pedigree with primary metabolic enzymes(1). However, the lineage of the enzyme chalcone isomerase (CHI) remained a quandary. In vascular plants, CHI-catalyzed conversion of chalcones to chiral (S)-flavano...

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Detalles Bibliográficos
Autores principales:	Ngaki, Micheline N., Louie, Gordon V., Philippe, Ryan N., Manning, Gerard, Pojer, Florence, Bowman, Marianne E., Li, Ling, Larsen, Elise, Wurtele, Eve Syrkin, Noel, Joseph P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880581/ https://www.ncbi.nlm.nih.gov/pubmed/22622584 http://dx.doi.org/10.1038/nature11009

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