Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach

Recombinant adeno-associated viruses are important vectors for retinal gene delivery. Currently utilized vectors have relatively slow onset and for efficient transduction it is necessary to deliver treatment subretinally, with the potential for damage to the retina. Amino-acid substitutions in the v...

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Detalles Bibliográficos
Autores principales: Mowat, FM, Gornik, KR, Dinculescu, A, Boye, SL, Hauswirth, WW, Petersen-Jones, SM, Bartoe, JT
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880610/
https://www.ncbi.nlm.nih.gov/pubmed/24225638
http://dx.doi.org/10.1038/gt.2013.64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880610/
https://www.ncbi.nlm.nih.gov/pubmed/24225638
http://dx.doi.org/10.1038/gt.2013.64

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