Cornel Iridoid Glycoside Attenuates Tau Hyperphosphorylation by Inhibition of PP2A Demethylation

Aim. The aim of the present study was to investigate the effect of cornel iridoid glycoside (CIG) on tau hyperphosphorylation induced by wortmannin (WT) and GF-109203X (GFX) and the underlying mechanisms. Methods. Human neuroblastoma SK-N-SH cells were preincubated with CIG (50, 100, and 200 µg/ml,...

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Detalles Bibliográficos
Autores principales: Yang, Cui-cui, Kuai, Xue-xian, Li, Ya-li, Zhang, Li, Yu, Jian-chun, Li, Lin, Zhang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880719/
https://www.ncbi.nlm.nih.gov/pubmed/24454482
http://dx.doi.org/10.1155/2013/108486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880719/
https://www.ncbi.nlm.nih.gov/pubmed/24454482
http://dx.doi.org/10.1155/2013/108486

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