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Cornel Iridoid Glycoside Attenuates Tau Hyperphosphorylation by Inhibition of PP2A Demethylation
Aim. The aim of the present study was to investigate the effect of cornel iridoid glycoside (CIG) on tau hyperphosphorylation induced by wortmannin (WT) and GF-109203X (GFX) and the underlying mechanisms. Methods. Human neuroblastoma SK-N-SH cells were preincubated with CIG (50, 100, and 200 µg/ml,...
Autores principales: | Yang, Cui-cui, Kuai, Xue-xian, Li, Ya-li, Zhang, Li, Yu, Jian-chun, Li, Lin, Zhang, Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880719/ https://www.ncbi.nlm.nih.gov/pubmed/24454482 http://dx.doi.org/10.1155/2013/108486 |
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