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Development and Evaluation of Gastroretentive Floating Tablets of an Antihypertensive Drug Using Hydrogenated Cottonseed Oil

The aim of the present work was to develop a gastroretentive floating tablet of Atenolol and investigate the effects of both hydrophilic and hydrophobic retardant on in vitro release. Atenolol is an antihypertensive drug with an oral bioavailability of only 50% because of its poor absorption from lo...

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Detalles Bibliográficos
Autores principales: Pawar, Harshal Ashok, Gharat, Pooja Ramchandra, Dhavale, Rachana Vivek, Joshi, Pooja Rasiklal, Rakshit, Pushpita Pankajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880749/
https://www.ncbi.nlm.nih.gov/pubmed/24455312
http://dx.doi.org/10.1155/2013/137238