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Coupled GTPase and remodeling ATPase activities form a checkpoint for ribosome export

Eukaryotic ribosomes are assembled by a complex pathway that extends from the nucleolus to the cytoplasm and is powered by many energy-consuming enzymes (1-3). Nuclear export is a key, irreversible step in pre-ribosome maturation(4-8), but mechanisms underlying the timely acquisition of export compe...

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Detalles Bibliográficos
Autores principales: Matsuo, Yoshitaka, Granneman, Sander, Thoms, Matthias, Manikas, Rizos-Georgios, Tollervey, David, Hurt, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880858/
https://www.ncbi.nlm.nih.gov/pubmed/24240281
http://dx.doi.org/10.1038/nature12731