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HE4 (WFDC2) gene overexpression promotes ovarian tumor growth

Selective overexpression of Human epididymal secretory protein E4 (HE4) points to a role in ovarian cancer tumorigenesis but little is known about the role the HE4 gene or the gene product plays. Here we show that elevated HE4 serum levels correlate with chemoresistance and decreased survival rates...

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Detalles Bibliográficos
Autores principales: Moore, Richard G., Hill, Emily K., Horan, Timothy, Yano, Naohiro, Kim, KyuKwang, MacLaughlan, Shannon, Lambert-Messerlian, Geralyn, Tseng, YiTang Don, Padbury, James F., Miller, M. Craig, Lange, Thilo S., Singh, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880958/
https://www.ncbi.nlm.nih.gov/pubmed/24389815
http://dx.doi.org/10.1038/srep03574