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Molecular Signaling Pathways Mediating Osteoclastogenesis Induced by Prostate Cancer Cells

BACKGROUND: Advanced prostate cancer commonly metastasizes to bone leading to osteoblastic and osteolytic lesions. Although an osteolytic component governed by activation of bone resorbing osteoclasts is prominent in prostate cancer metastasis, the molecular mechanisms of prostate cancer-induced ost...

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Detalles Bibliográficos
Autores principales: Rafiei, Shahrzad, Komarova, Svetlana V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881018/
https://www.ncbi.nlm.nih.gov/pubmed/24370273
http://dx.doi.org/10.1186/1471-2407-13-605