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Adeno-associated virus serotypes 9 and rh10 mediate strong neuronal transduction of the dog brain

Canine models have many advantages for evaluating therapy of human central nervous system (CNS) diseases. In contrast to nonhuman primate models, naturally occurring canine CNS diseases are common. In contrast to murine models, the dog's lifespan is long, its brain is large and the diseases aff...

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Detalles Bibliográficos
Autores principales: Swain, G P, Prociuk, M, Bagel, J H, O'Donnell, P, Berger, K, Drobatz, K, Gurda, B L, Haskins, M E, Sands, M S, Vite, C H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881028/
https://www.ncbi.nlm.nih.gov/pubmed/24131981
http://dx.doi.org/10.1038/gt.2013.54