Sustained relief of neuropathic pain by AAV-targeted expression of CBD3 peptide in rat dorsal root ganglion

The Ca(2+) channel-binding domain 3 (CBD3) peptide, derived from the collapsin response mediator protein 2 (CRMP-2), is a recently discovered voltage-gated Ca(2+) channel (VGCC) blocker with a preference for Ca(V)2.2. Rodent administration of CBD3 conjugated to cell penetrating motif TAT (TAT-CBD3)...

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Detalles Bibliográficos
Autores principales: Fischer, G, Pan, B, Vilceanu, D, Hogan, Q H, Yu, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881029/
https://www.ncbi.nlm.nih.gov/pubmed/24152582
http://dx.doi.org/10.1038/gt.2013.56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881029/
https://www.ncbi.nlm.nih.gov/pubmed/24152582
http://dx.doi.org/10.1038/gt.2013.56

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