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A Novel Synthetic Mycolic Acid Inhibits Bronchial Hyperresponsiveness and Allergic Inflammation in a Mouse Model of Asthma

PURPOSE: Recognition of microbes is important to trigger the innate immune system. Mycolic acid (MA) is a component of the cell walls of mycobacteria such as Mycobacterium bovis Bacillus Calmette-Guerin. MA has immunogenic properties, which may modulate the innate and adaptive immune response. This...

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Detalles Bibliográficos
Autores principales: Kim, Young-Joon, Kim, Ha-Jung, Jeong, Se Kyoo, Lee, Seung-Hwa, Kang, Mi-Jin, Yu, Ho-Sung, Jung, Young-Ho, Seo, Ju-Hee, Kim, Byoung-Ju, Yu, Jinho, Park, Seoung-Ju, Lee, Yong-Chul, Hong, Soo-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881406/
https://www.ncbi.nlm.nih.gov/pubmed/24404398
http://dx.doi.org/10.4168/aair.2014.6.1.83