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The neurotrophic hepatocyte growth factor attenuates CD8(+) cytotoxic T-lymphocyte activity
BACKGROUND: Accumulating evidence suggests a deleterious role for CD8(+) T cells in multiple sclerosis (MS) pathogenesis. We have recently reported that hepatocyte growth factor (HGF), a potent neuroprotective factor, limits CD4(+) T cell-mediated autoimmune neuroinflammation by promoting tolerogeni...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881506/ https://www.ncbi.nlm.nih.gov/pubmed/24344806 http://dx.doi.org/10.1186/1742-2094-10-154 |