The neurotrophic hepatocyte growth factor attenuates CD8(+) cytotoxic T-lymphocyte activity

BACKGROUND: Accumulating evidence suggests a deleterious role for CD8(+) T cells in multiple sclerosis (MS) pathogenesis. We have recently reported that hepatocyte growth factor (HGF), a potent neuroprotective factor, limits CD4(+) T cell-mediated autoimmune neuroinflammation by promoting tolerogeni...

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Detalles Bibliográficos
Autores principales: Benkhoucha, Mahdia, Molnarfi, Nicolas, Schneiter, Gregory, Walker, Paul R, Lalive, Patrice H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881506/
https://www.ncbi.nlm.nih.gov/pubmed/24344806
http://dx.doi.org/10.1186/1742-2094-10-154

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