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Aneuploidy: implications for protein homeostasis and disease

It has long been appreciated that aneuploidy – in which cells possess a karyotype that is not a multiple of the haploid complement – has a substantial impact on human health, but its effects at the subcellular level have only recently become a focus of investigation. Here, we summarize new findings...

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Detalles Bibliográficos
Autores principales: Oromendia, Ana B., Amon, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882044/
https://www.ncbi.nlm.nih.gov/pubmed/24396150
http://dx.doi.org/10.1242/dmm.013391