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Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases
Caenorhabditis elegans has a number of distinct advantages that are useful for understanding the basis for cellular and organismal dysfunction underlying age-associated diseases of protein misfolding. Although protein aggregation, a key feature of human neurodegenerative diseases, has been typically...
Autores principales: | Nussbaum-Krammer, Carmen I., Morimoto, Richard I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882046/ https://www.ncbi.nlm.nih.gov/pubmed/24396152 http://dx.doi.org/10.1242/dmm.013011 |
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