The unfolded protein response has a protective role in yeast models of classic galactosemia

Classic galactosemia is a human autosomal recessive disorder caused by mutations in the GALT gene (GAL7 in yeast), which encodes the enzyme galactose-1-phosphate uridyltransferase. Here we show that the unfolded protein response pathway is triggered by galactose in two yeast models of galactosemia:...

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Detalles Bibliográficos
Autores principales: De-Souza, Evandro A., Pimentel, Felipe S. A., Machado, Caio M., Martins, Larissa S., da-Silva, Wagner S., Montero-Lomelí, Mónica, Masuda, Claudio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882048/
https://www.ncbi.nlm.nih.gov/pubmed/24077966
http://dx.doi.org/10.1242/dmm.012641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882048/
https://www.ncbi.nlm.nih.gov/pubmed/24077966
http://dx.doi.org/10.1242/dmm.012641

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