Valproic acid silencing of ascl1b/Ascl1 results in the failure of serotonergic differentiation in a zebrafish model of fetal valproate syndrome

Fetal valproate syndrome (FVS) is caused by in utero exposure to the drug sodium valproate. Valproate is used worldwide for the treatment of epilepsy, as a mood stabiliser and for its pain-relieving properties. In addition to birth defects, FVS is associated with an increased risk of autism spectrum...

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Detalles Bibliográficos
Autores principales: Jacob, John, Ribes, Vanessa, Moore, Steven, Constable, Sean C., Sasai, Noriaki, Gerety, Sebastian S., Martin, Darren J., Sergeant, Chris P., Wilkinson, David G., Briscoe, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882053/
https://www.ncbi.nlm.nih.gov/pubmed/24135485
http://dx.doi.org/10.1242/dmm.013219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882053/
https://www.ncbi.nlm.nih.gov/pubmed/24135485
http://dx.doi.org/10.1242/dmm.013219

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