Transcriptional changes and developmental abnormalities in a zebrafish model of myotonic dystrophy type 1

Myotonic dystrophy type I (DM1) is a multi-system, autosomal dominant disorder caused by expansion of a CTG repeat sequence in the 3′UTR of the DMPK gene. The size of the repeat sequence correlates with age at onset and disease severity, with large repeats leading to congenital forms of DM1 associat...

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Detalles Bibliográficos
Autores principales: Todd, Peter K., Ackall, Feras Y., Hur, Junguk, Sharma, Kush, Paulson, Henry L., Dowling, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882056/
https://www.ncbi.nlm.nih.gov/pubmed/24092878
http://dx.doi.org/10.1242/dmm.012427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882056/
https://www.ncbi.nlm.nih.gov/pubmed/24092878
http://dx.doi.org/10.1242/dmm.012427

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