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Mapping differential interactomes by affinity purification coupled with data independent mass spectrometry acquisition
Characterizing changes in protein-protein interactions associated with sequence variants (e.g. disease-associated mutations or splice forms) or following exposure to drugs, growth factors or hormones is critical to understanding how protein complexes are built, localized and regulated. Affinity puri...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882083/ https://www.ncbi.nlm.nih.gov/pubmed/24162924 http://dx.doi.org/10.1038/nmeth.2702 |