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Exploiting the Synergy between Carboplatin and ABT-737 in the Treatment of Ovarian Carcinomas
Platinum drug-resistance in ovarian cancers mediated by anti-apoptotic proteins such as Bcl-xL is a major factor contributing to the chemotherapeutic resistance of recurrent disease. Consequently, concurrent inhibition of Bcl-xL in combination with chemotherapy may improve treatment outcomes for pat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882219/ https://www.ncbi.nlm.nih.gov/pubmed/24400068 http://dx.doi.org/10.1371/journal.pone.0081582 |