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Figla-Cre Transgenic Mice Expressing Myristoylated EGFP in Germ Cells Provide a Model for Investigating Perinatal Oocyte Dynamics

FIGLA (Factor in the germline, alpha) is a bHLH transcription factor expressed abundantly in female and less so in male germ cells. Mice lacking FIGLA do not form primordial follicles in the ovary and females are sterile, but there is no obvious phenotype in males. Using the Figla promoter to expres...

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Detalles Bibliográficos
Autores principales: Lin, Ruei-Shiuan, Jimenez-Movilla, Maria, Dean, Jurrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882233/
https://www.ncbi.nlm.nih.gov/pubmed/24400092
http://dx.doi.org/10.1371/journal.pone.0084477