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A Neutralization Epitope in the Hepatitis C Virus E2 Glycoprotein Interacts with Host Entry Factor CD81

The identification of a specific immunogenic candidate that will effectively activate the appropriate pathway for neutralizing antibody production is fundamental for vaccine design. By using a monoclonal antibody (1H8) that neutralizes HCV in vitro, we have demonstrated here that 1H8 recognized an e...

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Detalles Bibliográficos
Autores principales: Zhao, Zhong, Zhong, Lilin, Elrod, Elizabeth, Struble, Evi, Ma, Li, Yan, Hailing, Harman, Christine, Deng, Lu, Virata-Theimer, Maria Luisa, Liu, Peter, Alter, Harvey, Grakoui, Arash, Zhang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882236/
https://www.ncbi.nlm.nih.gov/pubmed/24400084
http://dx.doi.org/10.1371/journal.pone.0084346