Cargando…
A Neutralization Epitope in the Hepatitis C Virus E2 Glycoprotein Interacts with Host Entry Factor CD81
The identification of a specific immunogenic candidate that will effectively activate the appropriate pathway for neutralizing antibody production is fundamental for vaccine design. By using a monoclonal antibody (1H8) that neutralizes HCV in vitro, we have demonstrated here that 1H8 recognized an e...
Autores principales: | Zhao, Zhong, Zhong, Lilin, Elrod, Elizabeth, Struble, Evi, Ma, Li, Yan, Hailing, Harman, Christine, Deng, Lu, Virata-Theimer, Maria Luisa, Liu, Peter, Alter, Harvey, Grakoui, Arash, Zhang, Pei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882236/ https://www.ncbi.nlm.nih.gov/pubmed/24400084 http://dx.doi.org/10.1371/journal.pone.0084346 |
Ejemplares similares
-
Antibody-mediated synergy and interference in the neutralization of SARS-CoV at an epitope cluster on the spike protein
por: Zhong, Lilin, et al.
Publicado: (2009) -
Discrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralization
por: Deng, Lu, et al.
Publicado: (2014) -
Structural evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus
por: Deng, Lu, et al.
Publicado: (2013) -
A conserved epitope III on hepatitis C virus E2 protein has alternate conformations facilitating cell binding or virus neutralization
por: Deng, Lu, et al.
Publicado: (2021) -
Multiple epitopes of hepatitis B virus surface antigen targeted by human plasma‐derived immunoglobulins coincide with clinically observed escape mutations
por: Tarafdar, Sreya, et al.
Publicado: (2021)