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Matrix Stiffness Affects Endocytic Uptake of MK2-Inhibitor Peptides

In this study, the role of substrate stiffness on the endocytic uptake of a cell-penetrating peptide was investigated. The cell-penetrating peptide, an inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), enters a primary mesothelial cell line predominantly through caveol...

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Detalles Bibliográficos
Autores principales: Brugnano, Jamie L., Panitch, Alyssa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882240/
https://www.ncbi.nlm.nih.gov/pubmed/24400117
http://dx.doi.org/10.1371/journal.pone.0084821