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Activation of the Nrf2/HO-1 Antioxidant Pathway Contributes to the Protective Effects of Lycium Barbarum Polysaccharides in the Rodent Retina after Ischemia-Reperfusion-Induced Damage

Lycium barbarum polysaccharides (LBP), extracts from the wolfberries, are protective to retina after ischemia-reperfusion (I/R). The antioxidant response element (ARE)–mediated antioxidant pathway plays an important role in maintaining the redox status of the retina. Heme oxygenase-1 (HO-1), combine...

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Detalles Bibliográficos
Autores principales: He, Meihua, Pan, Hong, Chang, Raymond Chuen-Chung, So, Kwok-Fai, Brecha, Nicholas C., Pu, Mingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882254/
https://www.ncbi.nlm.nih.gov/pubmed/24400114
http://dx.doi.org/10.1371/journal.pone.0084800