Differential Roles of MAPK Kinases MKK3 and MKK6 in Osteoclastogenesis and Bone Loss

Bone mass is maintained by osteoclasts that resorb bone and osteoblasts that promote matrix deposition and mineralization. Bone homeostasis is altered in chronic inflammation as well as in post-menopausal loss of estrogen, which favors osteoclast activity that leads to osteoporosis. The MAPK p38α is...

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Detalles Bibliográficos
Autores principales: Boyle, David L., Hammaker, Deepa, Edgar, Meghan, Zaiss, Mario M., Teufel, Stefan, David, Jean Pierre, Schett, Georg, Firestein, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882259/
https://www.ncbi.nlm.nih.gov/pubmed/24400116
http://dx.doi.org/10.1371/journal.pone.0084818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882259/
https://www.ncbi.nlm.nih.gov/pubmed/24400116
http://dx.doi.org/10.1371/journal.pone.0084818

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