Cargando…

Protective Immunity against Lethal F. tularensis holarctica LVS Provided by Vaccination with Selected Novel CD8(+) T Cell Epitopes

Recently we described an unbiased bacterial whole-genome immunoinformatic analysis aimed at selection of potential CTL epitopes located in “hotspots” of predicted MHC-I binders. Applying this approach to the proteome of the facultative intra-cellular pathogen Francisella tularensis resulted in ident...

Descripción completa

Detalles Bibliográficos
Autores principales: Rotem, Shahar, Cohen, Ofer, Bar-Haim, Erez, Bar-On, Liat, Ehrlich, Sharon, Shafferman, Avigdor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882263/
https://www.ncbi.nlm.nih.gov/pubmed/24400128
http://dx.doi.org/10.1371/journal.pone.0085215