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Protective Immunity against Lethal F. tularensis holarctica LVS Provided by Vaccination with Selected Novel CD8(+) T Cell Epitopes
Recently we described an unbiased bacterial whole-genome immunoinformatic analysis aimed at selection of potential CTL epitopes located in “hotspots” of predicted MHC-I binders. Applying this approach to the proteome of the facultative intra-cellular pathogen Francisella tularensis resulted in ident...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882263/ https://www.ncbi.nlm.nih.gov/pubmed/24400128 http://dx.doi.org/10.1371/journal.pone.0085215 |