HCV Genomic RNA Activates the NLRP3 Inflammasome in Human Myeloid Cells

BACKGROUND: Elevated plasma levels of IL-1β and IL-18 from patients with hepatitis C virus (HCV) infection indicate a possible activation of inflammasome by HCV. METHODOLOGY/PRINCIPAL FINDINGS: To demonstrate whether HCV infection activates the inflammasome, we investigated inflammasome activation f...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Xu, Yongfen, Li, Hua, Tao, Wanyin, Xiang, Yu, Huang, Bing, Niu, Junqi, Zhong, Jin, Meng, Guangxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882267/
https://www.ncbi.nlm.nih.gov/pubmed/24400125
http://dx.doi.org/10.1371/journal.pone.0084953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882267/
https://www.ncbi.nlm.nih.gov/pubmed/24400125
http://dx.doi.org/10.1371/journal.pone.0084953

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