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Activation of cyclin-dependent kinase 5 mediates orofacial mechanical hyperalgesia

BACKGROUND: Cyclin-dependent kinase 5 (Cdk5) is a unique member of the serine/threonine kinase family. This kinase plays an important role in neuronal development, and deregulation of its activity leads to neurodegenerative disorders. Cdk5 also serves an important function in the regulation of nocic...

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Detalles Bibliográficos
Autores principales: Prochazkova, Michaela, Terse, Anita, Amin, Niranjana D, Hall, Bradford, Utreras, Elias, Pant, Harish C, Kulkarni, Ashok B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882292/
https://www.ncbi.nlm.nih.gov/pubmed/24359609
http://dx.doi.org/10.1186/1744-8069-9-66