Characterization of Striatal Neuronal Loss and Atrophy in the R6/2 Mouse Model of Huntington’s Disease

Striatal neuronal degeneration and loss is an important feature of human Huntington’s disease (HD). R6/2 HD mice recapitulate many features of human HD including striatal atrophy. While striatal neuronal atrophy and loss is reported in R6/2 HD mice the degree of neuronal loss and the characteristics...

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Detalles Bibliográficos
Autores principales: Dodds, Lindsay, Chen, Jianfang, Berggren, Kiersten, Fox, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
HD Models
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882322/
https://www.ncbi.nlm.nih.gov/pubmed/24459614
http://dx.doi.org/10.1371/currents.hd.48727b68b39b82d5fe350f753984bcf9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882322/
https://www.ncbi.nlm.nih.gov/pubmed/24459614
http://dx.doi.org/10.1371/currents.hd.48727b68b39b82d5fe350f753984bcf9

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