Loss of neurotrophin-3 from smooth muscle disrupts vagal gastrointestinal afferent signaling and satiation

A large proportion of vagal afferents are dependent on neurotrophin-3 (NT-3) for survival. NT-3 is expressed in developing gastrointestinal (GI) smooth muscle, a tissue densely innervated by vagal mechanoreceptors, and thus could regulate their survival. We genetically ablated NT-3 from developing G...

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Detalles Bibliográficos
Autores principales: Fox, Edward A., Biddinger, Jessica E., Baquet, Zachary C., Jones, Kevin R., McAdams, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2013
Materias:
Neural Control
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882559/
https://www.ncbi.nlm.nih.gov/pubmed/24068045
http://dx.doi.org/10.1152/ajpregu.00337.2013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882559/
https://www.ncbi.nlm.nih.gov/pubmed/24068045
http://dx.doi.org/10.1152/ajpregu.00337.2013

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