The DNA Damage Response: A Common Pathway in the Regulation of NKG2D and DNAM-1 Ligand Expression in Normal, Infected, and Cancer Cells

NKG2D and DNAM-1 are two activating receptors, present on the surface of NK cells and other cells of the immune system. Their ligands – MICA, MICB, ULBP1-6 for NKG2D, PVR/CD155 and Nectin-2/CD112 for DNAM-1 – can be constitutively expressed at low levels in some normal cells, but they are more often...

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Detalles Bibliográficos
Autores principales: Cerboni, Cristina, Fionda, Cinzia, Soriani, Alessandra, Zingoni, Alessandra, Doria, Margherita, Cippitelli, Marco, Santoni, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882864/
https://www.ncbi.nlm.nih.gov/pubmed/24432022
http://dx.doi.org/10.3389/fimmu.2013.00508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882864/
https://www.ncbi.nlm.nih.gov/pubmed/24432022
http://dx.doi.org/10.3389/fimmu.2013.00508

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