The retinoic acid receptor-α modulators ATRA and Ro415253 reciprocally regulate human IL-5+ Th2 cell proliferation and cytokine expression

BACKGROUND: Th2 cytokine responses are enhanced by all trans retinoic acid (ATRA), the bioavailable form of vitamin A. Retinoic acid receptor alpha (RARα) is the high affinity receptor for ATRA that mediates these pro-Th2 effects. We have previously characterized two major human Th2 subpopulations:...

Descripción completa

Detalles Bibliográficos
Autores principales: Wansley, Daniel L, Yin, Yuzhi, Prussin, Calman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882882/
https://www.ncbi.nlm.nih.gov/pubmed/24314292
http://dx.doi.org/10.1186/1476-7961-11-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882882/
https://www.ncbi.nlm.nih.gov/pubmed/24314292
http://dx.doi.org/10.1186/1476-7961-11-4

Ejemplares similares