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Expression of Activation-Induced Cytidine Deaminase Gene in B Lymphocytes of Patients with Common Variable Immunodeficiency

OBJECTIVE: Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by reduced serum level of IgG, IgA or IgM and recurrent bacterial infections. Class switch recombination (CSR) as a critical process in immunoglobulin production is defective in a group of CVID patients. Act...

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Detalles Bibliográficos
Autores principales: Abolhassani, Hassan, Farrokhi, Amir Salek, Pourhamdi, Shabnam, Mohammadinejad, Payam, Sadeghi, Bamdad, Moazzeni, Seyed-Mohammad, Aghamohammadi, Asghar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883376/
https://www.ncbi.nlm.nih.gov/pubmed/24427500