Pathway-GPS and SIGORA: identifying relevant pathways based on the over-representation of their gene-pair signatures

Motivation. Predominant pathway analysis approaches treat pathways as collections of individual genes and consider all pathway members as equally informative. As a result, at times spurious and misleading pathways are inappropriately identified as statistically significant, solely due to components...

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Detalles Bibliográficos
Autores principales: Foroushani, Amir B.K., Brinkman, Fiona S.L., Lynn, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2013
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883547/
https://www.ncbi.nlm.nih.gov/pubmed/24432194
http://dx.doi.org/10.7717/peerj.229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883547/
https://www.ncbi.nlm.nih.gov/pubmed/24432194
http://dx.doi.org/10.7717/peerj.229

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