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Development and characterization of a gastroretentive dosage form composed of chitosan and hydroxyethyl cellulose for alendronate
In this study, alendronate, the most commonly used biphosphonate for treating osteoporosis, was formulated as gastroretentive dosage form (GRDF) tablets to enhance its oral bioavailability. GRDF tablets were characterized with the effects of different molecular weights (MWs) of chitosan (CS) and hyd...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883582/ https://www.ncbi.nlm.nih.gov/pubmed/24403821 http://dx.doi.org/10.2147/DDDT.S52791 |