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Mycobacterium tuberculosis Ser/Thr Protein Kinase B Mediates an Oxygen-Dependent Replication Switch

The majority of Mycobacterium tuberculosis (Mtb) infections are clinically latent, characterized by drug tolerance and little or no bacterial replication. Low oxygen tension is a major host factor inducing bacteriostasis, but the molecular mechanisms driving oxygen-dependent replication are poorly u...

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Detalles Bibliográficos
Autores principales: Ortega, Corrie, Liao, Reiling, Anderson, Lindsey N., Rustad, Tige, Ollodart, Anja R., Wright, Aaron T., Sherman, David R., Grundner, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883633/
https://www.ncbi.nlm.nih.gov/pubmed/24409094
http://dx.doi.org/10.1371/journal.pbio.1001746