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Expression of SLC2A9 Isoforms in the Kidney and Their Localization in Polarized Epithelial Cells

BACKGROUND: Many genome-wide association studies pointed out that SLC2A9 gene, which encodes a voltage-driven urate transporter, SLC2A9/GLUT9 (a.k.a. URATv1), as one of the most influential genes for serum urate levels. SLC2A9 is reported to encode two splice variants: SLC2A9-S (512 amino acids) and...

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Detalles Bibliográficos
Autores principales: Kimura, Toru, Takahashi, Michi, Yan, Kunimasa, Sakurai, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883675/
https://www.ncbi.nlm.nih.gov/pubmed/24409316
http://dx.doi.org/10.1371/journal.pone.0084996