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Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties Contribute to Tumor Generation, Metastasis and Chemotherapy Resistance through Hypoxia-Resistant Metabolism

Cells with sphere forming capacity, spheroid cells, are present in the malignant ascites of patients with epithelial ovarian cancer (EOC) and represent a significant impediment to efficacious treatment due to their putative role in progression, metastasis and chemotherapy resistance. The exact mecha...

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Detalles Bibliográficos
Autores principales: Liao, Jianqun, Qian, Feng, Tchabo, Nana, Mhawech-Fauceglia, Paulette, Beck, Amy, Qian, Zikun, Wang, Xinhui, Huss, Wendy J., Lele, Shashikant B., Morrison, Carl D., Odunsi, Kunle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883678/
https://www.ncbi.nlm.nih.gov/pubmed/24409314
http://dx.doi.org/10.1371/journal.pone.0084941