mRNA Levels of Related Abcb Genes Change Opposite to Each Other upon Histone Deacetylase Inhibition in Drug-Resistant Rat Hepatoma Cells

The multidrug-resistant phenotype of tumor cells is acquired via an increased capability of drug efflux by ABC transporters and causes serious problems in cancer treatment. With the aim to uncover whether changes induced by epigenetic mechanisms in the expression level of drug transporter genes corr...

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Detalles Bibliográficos
Autores principales: Sike, Ádám, Nagy, Enikő, Vedelek, Balázs, Pusztai, Dávid, Szerémy, Péter, Venetianer, Anikó, Boros, Imre M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883685/
https://www.ncbi.nlm.nih.gov/pubmed/24409311
http://dx.doi.org/10.1371/journal.pone.0084915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883685/
https://www.ncbi.nlm.nih.gov/pubmed/24409311
http://dx.doi.org/10.1371/journal.pone.0084915

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