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mRNA Levels of Related Abcb Genes Change Opposite to Each Other upon Histone Deacetylase Inhibition in Drug-Resistant Rat Hepatoma Cells
The multidrug-resistant phenotype of tumor cells is acquired via an increased capability of drug efflux by ABC transporters and causes serious problems in cancer treatment. With the aim to uncover whether changes induced by epigenetic mechanisms in the expression level of drug transporter genes corr...
Autores principales: | Sike, Ádám, Nagy, Enikő, Vedelek, Balázs, Pusztai, Dávid, Szerémy, Péter, Venetianer, Anikó, Boros, Imre M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883685/ https://www.ncbi.nlm.nih.gov/pubmed/24409311 http://dx.doi.org/10.1371/journal.pone.0084915 |
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