Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues

Transposable elements (TEs) were discovered by Barbara McClintock in maize and have since been found to be ubiquitous in all living organisms. Transposition is mutagenic and organisms have evolved mechanisms to repress the activity of their endogenous TEs. Transposition in somatic cells is very low,...

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Detalles Bibliográficos
Autores principales: De Cecco, Marco, Criscione, Steven W., Peterson, Abigail L., Neretti, Nicola, Sedivy, John M., Kreiling, Jill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883704/
https://www.ncbi.nlm.nih.gov/pubmed/24323947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883704/
https://www.ncbi.nlm.nih.gov/pubmed/24323947

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