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Age-associated stresses induce an anti-inflammatory senescent phenotype in endothelial cells

Age is the greatest risk factor for cardiovascular disease. In addition, inflammation and age (senescence) have been linked at both the clinical and molecular levels. In general, senescent cells have been described as pro-inflammatory based on their senescence associated secretory phenotype (SASP)....

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Detalles Bibliográficos
Autores principales: Coleman, Paul R., Chang, Garry, Hutas, Gabor, Grimshaw, Matthew, Vadas, Mathew A., Gamble, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883707/
https://www.ncbi.nlm.nih.gov/pubmed/24334613