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Epigenetic pathways and glioblastoma treatment

Glioblastoma multiforme (GBM) is the most common malignant adult brain tumor. Standard GBM treatment includes maximal safe surgical resection with combination radiotherapy and adjuvant temozolomide (TMZ) chemotherapy. Alarmingly, patient survival at five-years is below 10%. This is in part due to th...

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Detalles Bibliográficos
Autores principales: Clarke, Jennifer, Penas, Clara, Pastori, Chiara, Komotar, Ricardo J, Bregy, Amade, Shah, Ashish H, Wahlestedt, Claes, Ayad, Nagi G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883781/
https://www.ncbi.nlm.nih.gov/pubmed/23807265
http://dx.doi.org/10.4161/epi.25440