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Homoharringtonine and omacetaxine for myeloid hematological malignancies
Homoharringtonine (HHT), a plant alkaloid with antitumor properties originally identified nearly 40 years ago, has a unique mechanism of action by preventing the initial elongation step of protein synthesis. HHT has been used widely in China for the treatment of chronic myeloid leukemia (CML), acute...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884015/ https://www.ncbi.nlm.nih.gov/pubmed/24387717 http://dx.doi.org/10.1186/1756-8722-7-2 |