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TIMP3 and CCNA1 hypermethylation in HNSCC is associated with an increased incidence of second primary tumors

BACKGROUND: Hypermethylation in the promoter regions is associated with the suppression of gene expression and has been considered a potential molecular marker for several tumor types, including head and neck squamous cell carcinomas (HNSCC). METHODS: To evaluate the gene hypermethylation profile as...

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Detalles Bibliográficos
Autores principales: Rettori, Marianna Marconato, de Carvalho, Ana Carolina, Longo, Ana Luiza Bomfim, de Oliveira, Cleyton Zanardo, Kowalski, Luiz Paulo, Carvalho, André Lopes, Vettore, André Luiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884019/
https://www.ncbi.nlm.nih.gov/pubmed/24359512
http://dx.doi.org/10.1186/1479-5876-11-316