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Functional Consequences of the Macrophage Stimulating Protein 689C Inflammatory Bowel Disease Risk Allele
BACKGROUND: Macrophage stimulating protein (MSP) is a serum growth factor that binds to and activates the receptor tyrosine kinase, Recepteur d'Origine Nantais (RON). A non-synonymous coding variant in MSP (689C) has been associated with genetic susceptibility to both Crohn's disease and u...
Autores principales: | Kauder, Steven E., Santell, Lydia, Mai, Elaine, Wright, Lilyan Y., Luis, Elizabeth, N'Diaye, Elsa N., Lutman, Jeff, Ratti, Navneet, Sa, Susan M., Maun, Henry R., Stefanich, Eric, Gonzalez, Lino C., Graham, Robert R., Diehl, Lauri, Faubion, William A., Keir, Mary E., Young, Judy, Chaudhuri, Amitabha, Lazarus, Robert A., Egen, Jackson G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884107/ https://www.ncbi.nlm.nih.gov/pubmed/24409221 http://dx.doi.org/10.1371/journal.pone.0083958 |
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